12 Best Grapefruit Cocktails

Grapefruit may not be the most celebrated fruit in the world of cocktails, but that’s exactly why we’re giving it the spotlight. We’ve curated a list of refreshing and unique grapefruit-based cocktails that are sure to quench your thirst.

From classic combinations like the Negroni and Salty Dog, to modern twists like the Paloma and Grapefruit Basil Mojito, our list has something for every taste bud. Whether you’re in the mood for a tangy and revitalizing drink or a sweet and sophisticated cocktail, grapefruit’s versatility as an ingredient ensures there’s a grapefruit-based drink out there for you.The world of grapefruit cocktails is rich with history, with some food historians tracing its origins back to Barbados.

Grapefruit Negroni

image source

A Negroni cocktail gets a vibrant twist with the addition of grapefruit juice, transforming the classic Italian-inspired drink into a stunning jewel-toned beverage. This unique variation of the traditional recipe, which typically consists of dry vermouth, gin, and Campari, substitutes Aperol for the bitters and incorporates fresh or bottled lemon juice to amplify its citrusy flavor profile. As a nod to the original’s elegant appeal, this grapefruit-infused Negroni is sure to delight even the most discerning palates.

Salty Dog

image source

The Salty Dog cocktail has been a staple of citrusy delights since its inception in the 1920s. This grapefruit mixed drink is remarkably similar to its Greyhound counterpart, yet it’s the addition of a salty rim that elevates the experience. The contrast between the simple syrup and grapefruit juice is perfectly balanced by this savory touch. When crafting a Salty Dog, you have the option to use either gin or vodka as your base spirit. For an added layer of complexity, consider incorporating pink grapefruit juice into the mix. To further sweeten the deal, simple syrup, agave syrup, or maple syrup can be used to round out the flavors. Interestingly, making your own simple syrup is a relatively simple process that requires little more than equal parts water and sugar. Of course, store-bought options are also readily available for those seeking a quicker solution. Finally, a spritz of lime juice adds a welcome brightness to this refreshing cocktail.

Sea Breeze

image source

The iconic Sea Breeze cocktail has captured hearts with its tantalizing blend of grapefruit and cranberry flavors, a perfect marriage of tanginess and sweetness. This refreshing concoction is brought to life by combining grapefruit juice, cranberry juice, and vodka. For those who crave a touch of sweetness, a hint of grenadine syrup, simple syrup, or agave syrup can be added to elevate the flavor profile. Interestingly, the original Sea Breeze recipe featured gin and grenadine syrup, offering a distinct variation on the classic formula. Typically, this delightful drink is served in a tall glass filled with ice cubes or crushed ice, accompanied by a wedge of lime for garnish.


image source

The Paloma, a timeless Mexican cocktail, is born when tequila meets grapefruit juice. This harmonious union is reminiscent of the gentle nature of doves, which ‘Paloma’ means in Spanish. While traditional recipes only require two ingredients – grapefruit juice and tequila – we’ve tweaked this classic to create a sweeter, fizzier delight.

To craft this revitalized Paloma, you’ll need tequila, fresh lime juice, grapefruit juice, simple syrup (agave nectar or maple syrup are suitable alternatives), and sparkling water or club soda. Once prepared, serve your creation over ice cubes or crushed ice in a cocktail glass with a salted rim.

Garnish with a maraschino cherry to complete the look. This refreshing drink is sure to please even the most discerning palates.

Pink Grapefruit Martini

image source

The classic vodka martini gets a refreshing twist when grapefruit juice is added, making it perfect for sizzling summer afternoons or evenings. To create this delightful cocktail, you can opt to squeeze fresh grapefruit juice at home or pick up a bottle from the juice aisle at your local grocery store or liquor shop. The essential ingredients include pink grapefruit juice, a splash of fresh lime juice, vodka, and a dash of orange liqueur (Triple Sec, Cointreau, or Grand Marnier). For an added layer of complexity, consider incorporating elderflower liqueur to give the drink a unique flavor profile. Combine all the ingredients in a cocktail shaker filled with ice cubes, shake vigorously to combine, then strain the mixture into a chilled martini glass.

Hemingway Daiquiri

image source

The Hemingway Daiquiri is a refreshing twist on the classic cocktail, featuring a combination of maraschino liqueur, lime, rum, and grapefruit juice that’s sure to quench your thirst. But did you know that this iconic drink has undergone changes over time? Initially, it called for double the amount of rum and no added sugar. However, the owners of El Floridita made some adjustments to create a more balanced flavor profile. Today’s official Hemingway Daiquiri recipe consists of white rum, maraschino liqueur, freshly squeezed lime juice, and grapefruit juice, making it a must-try for any cocktail enthusiast.

Brown Derby

image source

The Brown Derby cocktail is a timeless classic that originated in the 1930s at a Hollywood, California restaurant chain famous for its hat-shaped buildings. Although similar cocktails like the De Rigueur were listed in books from the 1920s, the Brown Derby’s unique twist lies in its use of bourbon instead of whiskey. We’re fond of modern variations that incorporate creative twists, such as combining rosemary with bourbon and grapefruit juice. What sets this recipe apart is its reliance on honey syrup to sweeten it, rather than simple syrup or sugar, giving it a distinct flavor profile.

Grapefruit Basil Mojito

image source

Innovate on the classic Cuban cocktail by substituting fresh mint leaves with fresh basil leaves, swapping sugar for agave syrup, and using pink grapefruit juice instead of lime juice. The result is a unique grapefruit basil mojito that still maintains its signature fizz thanks to club soda (or grapefruit soda). To complete the refreshing twist, garnish your drink with fresh basil leaves and a slice of grapefruit or ruby red grapefruit.


image source

In 2006, Katei Stipe, a New York-based bartender, created the Siesta cocktail, a refreshing blend of Italian and Mexican liqueurs. The unique combination of tequila and Campari yields a sweet and fruity drink that’s sure to please even the most discerning palates.

The recipe requires silver tequila, Campari, fresh grapefruit juice, lime juice, simple syrup (or agave syrup), and a grapefruit peel or ruby red grapefruit slice for garnish. Combine all ingredients in a cocktail shaker and shake until they’re ice-cold. Strain the mixture into a champagne glass or other cocktail glass to serve.


image source

While gin is traditionally used to make a classic Greyhound cocktail, you can also substitute it with vodka for a unique twist. The origins of the Greyhound date back to the early 1900s, when it was allegedly named after the famous bus line. To craft this refreshing grapefruit juice drink, you’ll need simple syrup – either homemade or store-bought from the mixers section of your local supermarket. Combine all the ingredients with ice cubes in a cocktail shaker and shake until well-chilled. Strain the Greyhound into a martini glass or another suitable vessel. If you prefer, you can serve it over rocks or crushed ice for added texture.

Grapefruit Shandy

image source

Get ready to indulge in the refreshing taste of a Grapefruit Shandy, a beer cocktail that’s been delighting enthusiasts for centuries. The concept of a shandy dates back to 19th-century Great Britain, where it was known as ‘shandygaff,’ a beer mixed with ginger ale or ginger beer. The French refer to this delightful concoction as the Panache. To create your Grapefruit Shandy, start with Modelo Especial, a crisp Mexican beer. Add a splash of tequila and grapefruit juice for a zesty twist. Finish it off with a slice of grapefruit as garnish, and you’re ready to toast to a perfect blend.

Grapefruit Margarita

image source

When we’re in the mood for something fresh and citrusy, we often find ourselves drawn to margaritas – especially when they’re infused with a twist of grapefruit. The sweet and tangy combination of lime and grapefruit juices creates a unique flavor profile that’s perfect for warm weather or anytime you need a little pick-me-up.

While traditional margaritas have been delighting palates since the 1930s, when they originated in Mexico, grapefruit margaritas are a more modern creation. However, once you try one, it’s easy to see why this refreshing cocktail has gained such popularity.

So, how do you make this tasty treat? Simply substitute some of the lime juice with freshly squeezed grapefruit juice and add it to your traditional margarita ingredients. For a grapefruit margarita that’s sure to please, you’ll need silver tequila (or reposado), grapefruit juice, Triple Sec (or Cointreau), agave nectar, and fresh limes.


Get ready to delight your loved ones with these scrumptious recipes. Whether you’re hosting a gathering or simply want to share a special moment, these dishes are sure to impress. Take a moment to share your thoughts and let’s hear from you!

Leave a Comment